Polynucleotide treatment

In my dermatology practice for aesthetic dermatology in Hamburg, I offer polynucleotide therapy for natural skin rejuvenation without volume enhancement. The active ingredients, derived from highly pure DNA, stimulate fibroblasts, promote collagen and elastin formation, improve hydration, and support cell renewal. This makes your skin appear smoother, more elastic, and fresher—reducing fine lines, loss of elasticity, and tired, dry skin.

Polynucleotide treatment in Hamburg – Natural skin rejuvenation without volume enhancement

Polynucleotide therapy is an innovative, science-based approach in aesthetic dermatology designed to sustainably improve skin quality. Rather than adding volume, this treatment focuses on targeted regeneration: it stimulates the body’s natural collagen and elastin production, strengthens skin structure, and enhances firmness and elasticity – for a refreshed, natural-looking result without overfilling.

Biostimulation at Cellular Level – Activating Collagen and Skin Renewal

Polynucleotides are highly purified, biocompatible DNA fragments used to activate fibroblasts (connective tissue cells). They promote collagen and elastin synthesis, improve skin hydration, support cellular repair, and provide antioxidant and anti-inflammatory benefits.

The result is smoother, firmer, and more even-looking skin, with visible improvement in fine lines, crepey skin, and loss of elasticity.

Who Is Polynucleotide Therapy Suitable For?

This treatment is particularly suitable for:

  • Early or advanced signs of skin aging

  • Loss of firmness and skin laxity

  • Dry, dull, or sensitive skin

  • Tired-looking complexion

  • Skin regeneration after laser treatments, microneedling, or chemical peels

  • Acne scars and superficial scars

It is appropriate for both women and men, especially from around the age of 40, and can also be used preventively.

Treatment Areas and Procedure

Polynucleotides are administered through fine microinjections into targeted areas. Common treatment zones include the face (especially under-eye area, cheeks, and forehead), neck, décolleté, perioral area, and hands.

A session typically takes 20–30 minutes. A series of 2–4 treatments at intervals of two to three weeks is usually recommended, followed by individualized maintenance sessions.

The procedure is generally well tolerated and requires no downtime. Mild redness or small swelling may occur but usually resolves quickly.

Polynucleotide therapy offers an effective option for patients seeking natural, regenerative skin rejuvenation in Hamburg.

treatment.perks

  • Natural skin rejuvenation without volume build-up – no “overfilling,” but genuine structural improvement.

  • Stimulation of collagen and elastin formation for greater firmness and elasticity.

  • Improved moisture retention (hydration) for plumper, fresher-looking skin.

  • Activation of cell renewal for sustainable regeneration.

  • Antioxidant and anti-inflammatory effect to strengthen the skin barrier

  • Visible improvement in fine lines and wrinkles

  • Suitable for the face, neck, décolleté, and hands

  • Very good tolerability and high biocompatibility

  • No or minimal downtime

  • Suitable for women and men, can also be used preventively

Schedule your appointment now

Our top priority is to provide you with personalized care. We take the time to understand your concerns and find tailored solutions for your skin health. With our flexible appointment scheduling, we want to ensure that you are treated at a time that works best for you.

Bookings not canceled 48 hours in advance must be paid for.

Make an appointment via Doctolib Contact

treatment.faq

No. While hyaluronic acid primarily builds volume and directly fills wrinkles, polynucleotides stimulate the body's own collagen and elastin production. The aim is to achieve a lasting improvement in skin quality and structure—without a volume effect.

Improved skin hydration is often visible after just a short time. The structural improvement in the skin due to new collagen formation develops gradually over several weeks and continues to increase over the course of the treatment series.

The treatment is generally well tolerated and does not require any downtime. Slight redness, swelling, or small wheals may occur at the injection sites, but these usually subside within a short time.

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